General Information
|
|
Product
|
GPCR GPR7 Antibody BIOTIN-Conjugated
|
Description
|
BIOTIN-Conjugated Neuropeptides B/W receptor type 1 Antibody
|
Verified Applications
|
ELISA, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Monkey
|
Immunogen
|
Synthetic peptide taken within amino acid region 1-50 on human neuropeptides B/W receptor type 1 protein.
|
Accession #
|
NCBI: NP_005276
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.5 µg/µl in antibody stabilization buffer
|
Immunoglobulin
|
IgG
|
Form
|
BIOTIN-Conjugated
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
ELISA
|
1:10,000
|
Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation
|
1:150
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P48145
|
Overview
|
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
|
Molecular Function
|
G-protein coupled receptor, Receptor, Transducer
|
Subcellular Location
|
Cell membrane; Multi-pass membrane protein
|
Expression
|
Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.
|
Structure
|
Belongs to the G-protein coupled receptor 1 family.
|
Alternative Nomenclature
|
G protein coupled receptor 7
GPR7
MGC129755
Neuropeptides B and W receptor 1
NPB and NPW receptor 1
NPBWR1
opioid somatostatin like receptor 7
|
|
|