General Information |
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Product |
IL18RAP Peptide |
Description |
Antigenic Blocking Peptide Interleukin-18 receptor accessory protein Antibody |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide taken within amino acid region 500-550 on human Interleukin-18 receptor accessory protein. |
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Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. |
Molecular Function |
Receptor activity |
Subcellular Location |
Membrane, Single-pass type I membrane protein |
Expression |
Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. |
Structure |
Belongs to the interleukin-1 receptor family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain. |
Alternative Nomenclature |
IL18RAP antibody Accessory protein like antibody AcPL antibody CD218 antigen-like family member B antibody CDw218b antibody IL-18R-beta antibody IL-18RAcP antibody IL-18Rbeta antibody IL-1R accessory protein-like antibody IL-1R7 antibody IL-1RAcPL antibody IL18RAP antibody IL18Rbeta antibody Interleukin 18 receptor accessory protein antibody Interleukin-1 receptor 7 antibody Interleukin-18 receptor beta antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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IL18RAP-101AP | |||
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IL18RAP-BIOTIN | |||
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IL18RAP-FITC | |||
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PC-IL18RAP | |||
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