General Information
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Product
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PDE10A2 Peptide
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Description
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Antigenic Blocking Peptide Phosphodiesterase 10A2 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 1-50 on human PDE10A2 protein.
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Accession #
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GenBank: AAD32596.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9Y233
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Overview
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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
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Molecular Function
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Hydrolase, metal-ion binding, cGMP binding
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Subcellular Location
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Cytoplasm
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Expression
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Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
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Structure
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Homodimer
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Alternative Nomenclature
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5''-cyclic phosphodiesterase 10A antibody
cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A antibody
cAMP and cAMP-inhibited cGMP 3'' antibody
FLJ11894 antibody
HSPDE10A antibody
Phosphodiesterase 10A antibody
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