General Information |
|
Product |
Pan PDE11A Antibody FITC-Conjugated |
Description |
FITC-Conjugated Cyclic Nucleotide Phosphodiesterase 11A1 Antibody N-epitope |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 100-150 on PDE11A protein, common to all PDE11A variants. |
Specificity | This antibody does not cross-react with any of the members of the PDE family. This antibody is common to all PDE11A variants including PDE11A1-PDE11A4. |
Accession # |
GenBank: CAB82573.1 |
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|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.68 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:250 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:250 |
Immunofluorescence |
1:250 |
Immunohistochemistry |
1:250 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. |
Molecular Function |
Hydrolase, metal-ion binding, cGMP binding |
Subcellular Location |
Cytoplasm |
Expression |
Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed i |
Alternative Nomenclature |
5''-cyclic-AMP and -GMP phosphodiesterase 11A antibody cAMP and cGMP cyclic nucleotide phosphodiesterase 11A antibody Cyclic nucleotide phosphodiesterase 11A1 antibody Dual 3' 5' cyclic AMP and GMP phosphodiesterase 11A antibody FLJ23693 antibody MGC133355 antibody MGC133356 antibody PDE 11A antibody pde11 antibody pde11a2 antibody Phosphodiesterase 11A antibody PPNAD2 antibody |
Protein information supplied by UniProt
Fabgennix PDE11A Antibody has been used in 14 Publications |
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Western Blot; Rat |
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Immunohistochemistry, Immunocompetition; Human |
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Western Blot Immunocompetition; Human, Mouse |
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Western Blot; Human |
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Immunohistochemistry; Human |
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Immunofluorescence, Western Blot; Rat |
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Immunohistochemistry; Human |
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Western Blot; Mouse |
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Immunohistochemistry, Immunodepletion, Western Blot; Rat |
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Immunofluorescence; Human |
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Immunofluorescence, Immunohistochemistry; Human |
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Immunohistochemistry, Western Blot; Human |
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Immunofluorescence, Western Blot; Mouse |
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Immunohistochemistry, Western Blot; Human |
Publishing research using PD11A-101AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PD11A-101AP | |||
|
P-PD11A | |||
|
PD11A-BIOTIN | |||
|
PC-PD11A | |||
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(c) FabGennix International Inc.