Subcellular Location
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Isoform 1: Cytoplasm › perinuclear region, Isoform 2: Cytoplasm, Cell projection, Isoform 4: Membrane; Peripheral membrane protein Isoform 6 : Cytoplasm › perinuclear region Isoform 7 : Cytoplasm. Membrane
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Expression
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Isoform 1 is widely expressed. Isoform 2 is abundant in liver, stomach, testis, thyroid and adrenal glands. It is also found in placenta, kidney, pancreas, ovary, uterus, skin, monocytes, mast cells, macrophages, as well as in bronchial smooth muscle. Isoform 6 is expressed at high levels in teh heart and small intestine. It is also found in the brain, kidney, spleen, colon, salivary gland, ovary and periphereal blood lymphocytes. Isoform 7 is expressed predominantly in skeletal muscle and brain and at lower levels in the testis. Isoform 7 is expressed in the brain. Found in specific neuronal subpopulations in cortex, spinal cord and cerebellum (at protein level).
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Alternative Nomenclature
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5''-cyclic phosphodiesterase 4A antibody
cAMP specific 3 5 cyclic phosphodiesterase 4A antibody
cAMP-specific 3'' antibody
DPDE2 antibody
dunce antibody
PDE46 antibody
PDE4A antibody
Phosphodiesterase 4 antibody
phosphodiesterase 4A cAMP specific antibody
phosphodiesterase E2 dunce homolog antibody
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