General Information |
|
Product |
PDE4B1 Peptide |
Description |
Antigenic Blocking Peptide cAMP-specific phosphodiesterase isoform PDE4B1 Antibody |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide selective only for PDE4B1 subtype variant. |
Accession # |
GenBank: AAL31763.1 |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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Uniprot # |
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Overview |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
Molecular Function |
Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding |
Expression |
Widely expressed. Isoform 3 expressed in brain, heart, lung and liver. Isoform 4 expressed in liver and brain. |
Alternative Nomenclature |
5''-cyclic phosphodiesterase 4B antibody cAMP-specific 3'' antibody cAMP-specific 3',5'-cyclic phosphodiesterase 4B antibody cAMP-specific phosphodiesterase-4 B isoform antibody DKFZp686F2182 antibody DPDE4 antibody dunce-like phosphodiesterase E4 antibody MGC126529 antibody PDE 4B antibody PDE IVB antibody PDE32 antibody PDE4B5 antibody Phosphodiesterase 4B antibody Phosphodiesterase 4B cAMP specific antibody |
Protein information supplied by UniProt
Fabgennix PDE4B1 Antibody has been used in 3 Publications |
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D. Mika, et. al. “PDE4B mediates local feedback regulation of B1-adrenergic cAMP signaling in a sarcolemmal compartment of cardiac myocytes.” Journal Cell Science. 2014 Mar 1;127(Pt 5):1033-42. PMC3937773
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Immunoprecipitation, Western Blot; Mouse |
Amanda, G. Vang, et al. "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." Biochemical Journal 456.3 (2013): 463-473. PMID24007532
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Western Blot; Mouse |
Hajjhussein, Hassan et al. “Changes in NMDA Receptor-Induced Cyclic Nucleotide Synthesis Regulate the Age-Dependent Increase in PDE4A Expression in Primary Cortical Cultures.” Brain research 1149 (2007): 58–68. PMC2720317
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Immunoprecipitation, Western Blot; Human |
Publishing research using PD4B1-261AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
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PD4B1-261AP | |||
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PD4B1-FITC | |||
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PD4B1-BIOTIN | |||
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PC-PD4B1 | |||
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