General Information |
|
Product |
PDE4D7 Peptide |
Description |
Antigenic Blocking Peptide cAMP-specific phosphodiesterase PDE4D7 |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant. |
Accession # |
GenBank: AF536978.1 |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
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|
Uniprot # |
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Overview |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
Molecular Function |
Hydrolase, 3',5'-cyclic-nucleotide phosphodiesterase activity, ATPase binding |
Subcellular Location |
Cytoplasm. Membrane. Cytoplasm › cytoskeleton. Cytoplasm › cytoskeleton › microtubule organizing center › centrosome. Apical cell membrane |
Expression |
Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis. |
Structure |
Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Binds ARRB2. Interacts with PDE4DIP (By similarity). Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1). Interacts (via N-terminal region) with SHANK2 (via proline-rich region); the interaction is increased in a PKA-dependent manner. |
Alternative Nomenclature |
DPDE3 antibody HSPDE4D antibody PDE43 antibody PDE4D antibody Phosphodiesterase 4D antibody Phosphodiesterase 4D cAMP-specific antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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PD4D7-471AP | |||
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PD4D7-FITC | |||
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PD4D7-BIOTIN | |||
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PC-PD4D7 | |||
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