General Information |
|
Product |
Phospho PDE10A Antibody BIOTIN |
Description |
BIOTIN-Conjugated Phosphorylated Phosphodiesterase 10A Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Mouse, Rat |
Immunogen |
Phosphorylated synthetic MAP common to all PDE10A variants. Taken within amino acid region 1-50 on human PDE10A protein. |
Specificity | This antibody will detect only phosphorylated PDE10A protein. |
Accession # |
GenBank: AAD32596.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.7 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. |
Molecular Function |
Hydrolase, metal-ion binding, cGMP binding |
Subcellular Location |
Cytoplasm |
Expression |
Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum. |
Structure |
Homodimer |
Alternative Nomenclature |
5''-cyclic phosphodiesterase 10A antibody cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A antibody cAMP and cAMP-inhibited cGMP 3'' antibody FLJ11894 antibody HSPDE10A antibody PDE 10A antibody Pde10a antibody Phosphodiesterase 10A antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-PPD10A | |||
|
PPD10A-140AP | |||
|
PPD10A-FITC | |||
|
PC-PPD10A | |||
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