General Information |
|
Product |
Phospho-PDE11A (S117) Antibody FITC |
Description |
FITC-Conjugated Phosphorylated Cyclic Nucleotide Phosphodiesterase 11A Antibody |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 75-125 on PDE11A protein. Phosphorylated Ser 117. |
Accession # |
NCBI: NP_543169 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.69 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:250 |
Immunofluorescence |
1:250 |
Immunohistochemistry |
1:250 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. |
Molecular Function |
Hydrolase, metal-ion binding, cGMP binding |
Subcellular Location |
Cytoplasm |
Expression |
Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed in adrenal cortex. |
Alternative Nomenclature |
5''-cyclic-AMP and -GMP phosphodiesterase 11A antibody cAMP and cGMP cyclic nucleotide phosphodiesterase 11A antibody cGMP phosphodiesterase 11A antibody Cyclic nucleotide phosphodiesterase 11A1 antibody Dual 3' 5' cyclic AMP and GMP phosphodiesterase 11A antibody Dual 3'' antibody phosphodiesterase 11A antibody FLJ23693 antibody MGC133355 antibody MGC133356 antibody PDE 11A antibody pde11 antibody PDE11A antibody PDE11A1 antibody pde11a2 antibody Phosphodiesterase 11A antibody PPNAD2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
PPD11A-140AP | |||
|
P-PPD11A | |||
|
PPD11A-BIOTIN | |||
|
PC-PPD11A | |||
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