General Information |
|
Product |
RIPK3 Peptide |
Description |
Antigenic Blocking Peptide Receptor-interacting Serine/Threonine-protein kinase 3 Antibody C-epitope |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic Peptide |
Accession # |
NCBI: NP_006862.2 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. |
Molecular Function |
Kinase, Serine/threonine-protein kinase, Transferase |
Subcellular Location |
Cytoplasm, Cell membrane, Mitochondrion |
Expression |
Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers. |
Structure |
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Contains 1 protein kinase domain. |
Alternative Nomenclature |
Receptor interacting protein 3 antibody Receptor interacting serine threonine kinase 3 antibody Receptor-interacting protein 3 antibody RIP 3 antibody RIP like protein kinase 3 antibody RIPK 3 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
RIPK3-301AP | |||
|
RIPK3.301-FITC | |||
|
RIPK3.301-BIOTIN | |||
|
PC-RIPK3 | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.