General Information |
|
Product |
RUNX3 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Runt-related transcription factor 3 Antibody N-epitope |
Verified Applications |
ELISA, IMM, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 1-50 on human Runt-related transcription factor 3 protein. |
Accession # |
NCBI: NP_001026850.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.52-0.53 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. |
Molecular Function |
ATP binding, RNA polymerase II regulatory region sequence-specific DNA binding |
Subcellular Location |
Nucleus, cytoplasm |
Structure |
Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain. DNA-binding is increased by heterodimerization. Interacts with TLE1 and SUV39H1. |
Alternative Nomenclature |
Acute myeloid leukemia 2 protein antibody AML2 antibody CBF alpha 3 antibody CBFA 3 antibody Core binding factor alpha 3 subunit antibody core binding factor antibody Core binding factor runt domain alpha subunit 3 antibody Core-binding factor subunit alpha-3 antibody FLJ34510 antibody MGC16070 antibody Oncogene AML 2 antibody PEA2 alpha C antibody PEBP2 alpha C antibody Pebp2a3 antibody PEBP2aC antibody Polyomavirus enhancer binding protein 2 alpha C subunit antibody runt domain alpha subunit 3 antibody runt related transcription factor 3 antibody RUNX 3 antibody SL3 3 enhancer factor 1 alpha C subunit antibody SL3/AKV core binding factor alpha C subunit antibody Transcription factor AML2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
RUNX3-301AP | |||
|
P-RUNX3.301 | |||
|
RUNX3.301-BIOTIN | |||
|
PC-RUNX3 | |||
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