General Information
|
|
Product
|
Src Antibody BIOTIN-Conjugated
|
Description
|
BIOTIN-Conjugated Proto-oncogene tyrosine-protein kinase Src Antibody N-epitope
|
Verified Applications
|
ELISA, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 200-300 on human Src protein.
|
Accession #
|
NCBI: NP_005408.1
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.56-0.60 µg/µl in antibody stabilization buffer
|
Form
|
BIOTIN-Conjugated
|
Clonality
|
Polyclonal
|
Determinant
|
N-epitope
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunoprecipitation
|
1:250
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P12931
|
Overview
|
Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis migration, and transformation
|
Molecular Function
|
ATP binding, ephrin receptor binding, heme binding, ion channel binding, enzyme binding, growth factor receptor binding, integrin binding, kinase activity
|
Subcellular Location
|
Cell membrane, mitochondrion inner membrane, nucleus, cytoplasm (Note: Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and SH3 domain.)
|
Expression
|
Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues.
|
Alternative Nomenclature
|
ASV antibody
Avian sarcoma virus antibody
c SRC antibody
CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody
EC 2.7.10.2 antibody
Neuronal CSRC tyrosine specific protein kinase antibody
Neuronal SRC antibody
Oncogene SRC antibody
p60 Src antibody
Proto oncogene tyrosine protein kinase Src antibody
SRC Oncogene antibody
SRC proto oncogene non receptor tyrosine kinase antibody
SRC1 antibody
vsrc avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody
|
|
|