General Information
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Product
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TUFM Antibody BIOTIN
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Description
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BIOTIN-Conjugated Elongation factor Tu, mitochondrial Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 325-375 on human Elongation factor Tu, mitochondrial.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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BIOTIN-Conjugated
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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P49411
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Overview
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Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.
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Molecular Function
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GTPase activity
GTP binding
RNA binding
translation elongation factor activity
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Subcellular Location
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Mitochondrion
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Alternative Nomenclature
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COXPD4 antibody
EF Tu antibody
EF-Tu antibody
EF-TuMT antibody
EFTu antibody
EFTuMT antibody
Elongation factor Tu antibody
Elongation factor Tu mitochondrial antibody
mitochondrial antibody
P43 antibody
Tu translation elongation factor, mitochondrial antibody
Tufm antibody
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