General Information
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Product
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CD3 Gamma Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated T-cell surface glycoprotein CD3 gamma chain Antibody
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Verified Applications
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ELISA, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 131-181 on human T-cell surface glycoprotein CD3 gamma protein.
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Accession #
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NCBI: NP_000064.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P09693
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Overview
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The CD3 complex mediates signal transduction.
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Molecular Function
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Protein heterodimerization activity; T cell receptor binding; Receptor signaling complex scaffold activity; Transmembrane signaling receptor activity
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Subcellular Location
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Membrane; Single-pass type I membrane protein
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Structure
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The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
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Alternative Nomenclature
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CD3 gamma antibody
CD3g antibody
CD3g antigen gamma polypeptide (TiT3 complex) antibody
CD3g antigen gamma polypeptide antibody
CD3g molecule gamma (CD3 TCR complex) antibody
T-cell receptor T3 gamma chain antibody
T-cell surface glycoprotein CD3 gamma chain antibody
T3G antibody
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