General Information
Product
DCC Positive Control
Description
Western Blot Positive Control Netrin Receptor DCC Antibody
Verified Applications
WB
Physical Properties
Quantity
5 Applications
Volume
Inquire
Form
Western Blot Positive Control
Storage
-20°C for long term storage
Application Protocol
Western Blot
1:500
Protein
Uniprot #
P43146
Overview
Receptor for netrin required for axon guidance; may trigger signaling for axon repulsion; acts as a dependence receptor required for apoptosis induction; tumor suppressor gene.
Molecular Function
netrin receptor activity; transcription coactivator activity; transmembrane signaling receptor activity; Developmental protein
Subcellular Location
axon; cytosol; plasma membrane
Expression
Found in axons of the central and peripheral nervous system; differentiated cell types of the intestine
Structure
Belongs to the immunoglobulin superfamily. DCC family; Contains 6 fibronectin type-III domains; Contains 4 Ig-like C2-type (immunoglobulin-like) domains
Alternative Nomenclature
Colorectal cancer related chromosome sequence 18 antibody
CRC 18 antibody
CRCR 1 antibody
DCC antibody
Deleted in colorectal cancer protein antibody
Immunoglobulin superfamily DCC subclass member 1 antibody
Netrin receptor DCC antibody
Tumor suppressor protein DCC antibody
Protein information supplied by UniProt
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