Mediates the vitamin K-dependent carboxylation of glutatmate residues to calcium-binding gamma-carboxyglutamate residues with the concomitant converstion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
Molecular Function
gamma-glutamyl carboxylase activity; Lyase
Subcellular Location
Endoplasmic Reticulum membrane; Multi-pass membrane protein