General Information
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Product
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LILRB3 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 580-631 on human LILRB3 protein.
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Specificity |
This antibody will detect all three isoforms of human LILRB3 protein. |
Accession #
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NCBI: NP_001074919.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.74 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:20,000
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ELISA
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1:20,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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O75022
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Overview
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May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
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Molecular Function
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Receptor, Receptor activity, transmembrane signaling receptor activity
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Subcellular Location
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Cell membrane; Single-pass type I membrane protein
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Expression
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Detected in monocytes and B-cells
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Alternative Nomenclature
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CD85 antigen like family member A antibody
HL9 antibody
IL T5 antibody
Immunoglobulin like transcript 5 antibody
LIR 3 antibody
MGC138403 antibody
Monocyte inhibitory receptor HL9 antibody
PIRB antibody
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