General Information
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Product
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MEK1 Positive Control
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Description
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Western Blot Positive Control Mitogen-activated protein kinase kinase 1 Antibody
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Verified Applications
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WB
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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Q02750
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Overview
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Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.
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Molecular Function
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Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase
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Subcellular Location
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Cytoplasm, Cytoskeleton, Membrane, Nucleus
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Expression
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Widely expressed, with extremely low levels in brain.
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Structure
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The proline-rich region localized between residues 270 and 307 is important for binding to RAF1 and activation of MAP2K1/MEK1.
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Alternative Nomenclature
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Dual specificity mitogen activated protein kinase kinase 1 antibody
ERK activator kinase 1 antibody
MAP kinase/Erk kinase 1 antibody
MAP2K1 antibodyMAPKK 1 antibody
MAPKK1 antibody
MEKK1 antibody
Mitogen activated protein kinase kinase 1 antibody
MKK1 antibodyPRKMK1 antibody
Protein kinase mitogen activated, kinase 1 antibody
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