General Information
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Product
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PDE1A Antibody
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Description
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Affinity Purified Phosphodiesterase 1A Antibody C-epitope
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Verified Applications
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CM, ELISA, ICC, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 51-101 on human PDE1A protein.
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Specificity |
This antibody will not label other PDE family members. This antibody will label all PDE1 variants including PDE1A1, PDE1A3, PDE1A5. |
Accession #
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NCBI: NP001009978.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.6 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunocytochemistry
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1:200
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Immunofluorescence
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1:200
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Immunohistochemistry
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1:200
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Immunoprecipitation
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1:200
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Western Blot
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1:500-1:1,000
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Protein
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Uniprot #
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Q9JLL9
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Overview
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Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
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Molecular Function
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Hydrolase, calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity, metal ion binding
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Subcellular Location
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Cytosol
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Expression
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Several tissues, including brain, kidney, testes and heart.
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Structure
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Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
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Alternative Nomenclature
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3' 5' cyclic nucleotide phosphodiesterase antibody
61 kDa Cam PDE antibody
Calcium/calmodulin dependent 3' 5' cyclic nucleotide phosphodiesterase 1A antibody Calcium/calmodulin-dependent 3'' antibody
Calmodulin-dependent Phosphodiesterase antibody
Cam PDE 1A antibody
HSPDE1A antibody
MGC26303 antibody
PDE1A antibody
Phosphodiesterase 1A antibody
Phosphodiesterase 1A calmodulin dependent antibody
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