General Information
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Product
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Phospho AKT1 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Rac protein kinase-alpha Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Bird, Bovine, Human, Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 430-480 on human Rac protein kinase-alpha protein.
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Accession #
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GenBank: AAA36539.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P31749
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Overview
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One of 3 serine/threonine-protein kinases (AKT1-AKT3) regulates many processes including metabolism, proliferation, cell survival, growth and angiogenesis.
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Molecular Function
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Developmental protein; Kinase; Serine/threonine-protein kinase; Transferase
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Subcellular Location
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Cytoplasm; Nucleus; Cell membrane
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Expression
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Expressed in prostate cancer and all human cell types.
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Structure
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Interacts with and phosphorylated by PDPK1. Interacts with several proteins invovled in phosphorylation and ubiquitination
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Alternative Nomenclature
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AKT 1 antibody
C AKT antibody
MGC9965 antibody
MGC99656 antibody
Oncogene AKT1 antibody
PKB antibody
PKB-ALPHA antibody
PRKBA antibody
Protein Kinase B Alpha antibody
Protein kinase B antibody
Proto-oncogene c-Akt antibody
RAC Alpha antibody
RAC antibody
RAC PK Alpha antibody
RAC Serine/Threonine Protein Kinase antibody
RAC-PK-alpha antibody
vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
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