General Information |
|
Product |
DAPK2 Peptide |
Description |
Antigenic Blocking Peptide Death-associated protein kinase 2 Antibody |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide take within amino acid region 300-350 on mouse Death-associated protein kinase 2 protein. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capable of regulating both type I apoptotic and type II autophagic cell death signals. |
Molecular Function |
ATP binding calmodulin binding identical protein binding protein serine/threonine kinase activity |
Subcellular Location |
Cytoplasm autophagosome lumen |
Expression |
Expressed in peritubular interstitial cells of the renal cortex (PubMed:24906443). Isoform 1 is found in the adult brain while isoform 2 is expressed in brains of embryos and young mice (at protein level) (PubMed:21408167). |
Structure |
The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core. |
Alternative Nomenclature |
DAK2 antibody DAP kinase 2 antibody DAP kinase related protein 1 antibody DAP kinase related protein 1 beta isoform antibody DAP-kinase-related protein 1 antibody DAPK2 antibody Death associated protein kinase 2 antibody DRP 1 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
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DAPK2-201AP | |||
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PC-DAPK2 | |||
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DAPK2-FITC | |||
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DAPK2-BIOTIN | |||
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