General Information |
|
Product |
PRP19 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated pre-mRNA-processing factor 19 Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 200-300 on rat PRP19F protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.50-0.75 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:2,000 |
ELISA |
1:2,000 |
Western Blot |
1:500-1:1,000 |
|
|
Uniprot # |
|
Overview |
Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. |
Molecular Function |
Ligase, DNA binding, ubiquitin-ubiquitin ligase activity |
Structure |
Homotetramer. Component of the Prp19 complex/PRP19C/Nineteen complex/NTC and related complexes described as PRP19-CDC5L splicing complex and PSO4 complex. A homotetramer of PRPF19, CDC5L, PLRG1 and BCAS2 constitute the core of those complexes. The interaction with CDC5L, PLRG1 and BCAS2 is direct within this core complex. |
Alternative Nomenclature |
hPso4 antibody NMP200 antibody Nuclear matrix protein 200 antibody pre mRNA processing factor 19 antibody PRP19 antibody PRP19/PSO4 homolog antibody PRPF19 antibody PSO4 antibody psoralen 4 antibody Senescence evasion factor antibody SNEV antibody UBOX4 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-PRP19F | |||
|
PRP19F-101AP | |||
|
PRP19F-FITC | |||
|
PC-PRP19F | |||
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