General Information
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Product
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ETS1 associated protein II Antibody
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Description
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Affinity Purified tyrosyl-DNA phosphodiesterase 2 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 330-360 on human Tyrosyl-DNA phosphodiesterase protein.
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Accession #
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NCBI: NP_057698.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.58 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
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1:1,000
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Protein
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Uniprot #
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O95551
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Overview
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DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue.
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Molecular Function
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5'-tyrosyl-DNA phosphodieseterase activity, magnesium ion binding, manganese ion binding, nuclease activity, transcription corepressor activity, single-stranded DNA binding
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Subcellular Location
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nucleus, PML body, cytoplasm
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Expression
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Widely expressed
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Alternative Nomenclature
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5'-tyrosyl-DNA phosphodiesterase antibody
AD 022 antibody
dJ30M3.3 antibody
EAP 2 antibody
ETS 1 associated protein 2 antibody
RP1-30M3.3 antibody
TRAF and TNF receptor associated protein antibody
TTRAP antibody
Tyr DNA phosphodiesterase 2 antibody
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