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General Information
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Product
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Phospho-KIRREL Positive Control
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Description
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Western Blot Positive Control kin of IRRE-like protein 1 Antibody C-epitope
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Verified Applications
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WB
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Accession #
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NCBI: NP_060710.3
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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| Concentration |
The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel. |
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Protein
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Uniprot #
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Q80W68
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Overview
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Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
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Molecular Function
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Myosin Binding
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Subcellular Location
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Cell membrane; Single-pass type I membrane protein
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Expression
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Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.
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Structure
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Interacts with TJP1/ZO-1 and with NPHS2/podocin (via the C-terminus). Interacts with NPHS1/nephrin (via the Ig-like domains); this interaction is dependent on KIRREL glycosylation. Homodimer (via the Ig-like domains). Interacts when tyrosine-phosphorylated with GRB2 (By similarity).
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Alternative Nomenclature
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FLJ10845 antibody
Kin of IRRE like protein 1 antibody
Kirrel antibody
NEPH1 antibody
Nephrin like protein 1 antibody
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Phospho-KIRREL Antibody
Phospho-KIRREL Antibody FITC
Phospho-KIRREL Blocking Peptide
Phospho-KIRREL Antibody BIOTIN
