General Information
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Product
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NKG2D Antibody Affinity Purified
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Description
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Affinity Purified NKG2-D type II integral membrane protein Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Bovine, Human, Monkey, Panda
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Immunogen
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Synthetic peptide taken within amino acid region 180-230 on rat NKG2D protein.
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Accession #
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NCBI: NP_598196.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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O70215
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Overview
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Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells
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Molecular Function
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MHC class Ib receptor activity
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Subcellular Location
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Cell membrane, Membrane
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Expression
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Expressed by natural killer cells and by resting thoracic duct CD4+ and CD8+ T-cells, but not by thymocytes or other hemopoietic cells. Expressed by DC cells
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Alternative Nomenclature
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CD314 antibody
D12S2489E antibody
Killer cell lectin like receptor subfamily K member 1 antibody
KLR antibody
NK cell receptor D antibody
NK lectin-like receptor antibody
NKG2 D activating NK receptor antibody
NKLLR antibody
NKR P2 antibody
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