General Information
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Product
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CXCR2 Antibody
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Verified Applications
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CM, ELISA, ICC/IF, IHC-Fr, IHC-P, IP, FC, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide:
EDLSNYSYSSTLPPFLLDAAPC
Corresponding to amino acids 18-39 of Human CXCR2.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Isotype |
IgG |
Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:200
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:200
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Immunofluorescence
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1:200
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Immunohistochemistry
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1:200
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Immunoprecipitation
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1:250
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Western Blot
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1:500 Predicted molecular weight: 55 kDa
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Protein
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Uniprot #
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P25025
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Overview
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Receptor for interleukin-8, binding of IL-8 to the receptor causes the activation of neutrophils. This response is mediated by a G-protein which activates a phosphatidyinositol-calcium second messenger system.
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Molecular Function
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G-Protein coupled receptor, Transducer, chemokine receptor activity
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Subcellular Location
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Cell membrane; Multi-pass membrane protein
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Expression
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Up-regulated by CREB3
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Structure
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Binds to HIV-1 Tat and interacts with ARRB1
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Alternative Nomenclature
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C-X-C chemokine receptor type 2 antibody
CD 182 antibody
CD182 antigen antibody
CDw128b antibody
Chemokine (CXC) receptor 2 antibody
CMKAR2 antibody
CXCR2 antibody
GRO/MGSA receptor antibody
High affinity interleukin-8 receptor B antibody
IL8R B antibody
IL8R2 antibody
IL8RA antibody
Interleukin 8 receptor, beta antibody
Interleukin 8 receptor, type 2 antibody
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