Lin28 Blocking Peptide

General Information

Product

Lin28 Peptide

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid sequence 1-60 on Lin28A sequence.

Accession #

GenBank: AAH28566.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q9H9Z2

Overview

Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Association with translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing mRNA's

Molecular Function

DNA binding, mRNA binding, zinc ion binding, miRNA binding, RNA binding

Subcellular Location

Cytoplasm, nucleus, nucleolus. (Note: nucleolar localization observed in 10-15% of nuclei in differentiated byotubes. Shuttles between cytoplasm and nucleus. Localizes to cytoplasmic processing bodies and stress granules)

Expression

Expressed in embryonic stem cells (ES cells), placenta and testis.

Alternative Nomenclature

AL024421 antibody

CSDD1 antibody

FLJ12457 antibody

Lin 28 antibody

Protein lin-28 homolog A antibody

RNA binding protein lin 28 antibody

Tex17 antibody

ZCCHC1 antibody

Zinc finger CCHC domain containing 1 antibody