General Information |
|
Product |
P2Y12 Antibody FITC-Conjugated |
Description |
FITC-Conjugated P2Y purinoceptor 12 Antibody |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Chimpanzee, Human, Monkey, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 300-342 on human P2Y12 protein. |
Accession # |
NCBI: NP_795345.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.57-0.68 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Serves as a receptor for ADP and ATP that is coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. It is necessary for platelet aggregation and blood coagulation. |
Molecular Function |
G-protein coupled receptor, Transducer, ADP-receptor activity |
Subcellular Location |
Cell membrane; Multipass membrane protein |
Expression |
It is highly expressed in the platelets with lower levels of expression found in the brain, and is also expressed in the spinal cord and fetal brain. The lowest levels of expression are found in the lung, appendix, pituitary and adrenal gland. |
Alternative Nomenclature |
ADP glucose receptor antibody ADPG R antibody BDPLT8 antibody G protein coupled receptor SP1999 antibody Gi coupled ADP receptor HORK 3 antibody HORK3 antibody P2RY12 antibody P2T(AC) antibody P2Y 12 antibody P2Y purinoceptor 12 antibody P2Y(12)R antibody P2Y(AC) antibody P2Y(ADP) antibody P2Y(cyc) antibody P2Y12 antibody P2Y12 platelet ADP receptor antibody Purinergic receptor P2RY12 antibody Purinergic receptor P2Y G protein coupled 12 antibody Putative G protein coupled receptor antibody SP1999 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P2Y12-1201AP | |||
|
P-P2Y12 | |||
|
P2Y12R-BIOTIN | |||
|
PC-P2Y12R | |||
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