General Information |
|
Product |
CTLA4 Antibody BIOTIN |
Description |
BIOTIN-Conjugated Cytotoxic T-lymphocyte protein 4 Antibody |
Verified Applications |
ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 150-200 on CTLA4 protein. |
Accession # |
GenBank: AAL07473.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.7 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family lingands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory correceptor CD28. |
Molecular Function |
Adaptive Immunity |
Subcellular Location |
Cell membrane; Single pass type I membrane protein |
Expression |
Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory correceptor, on the cell surface following activation. |
Structure |
Homodimer; disfulfide-linked |
Alternative Nomenclature |
CD 152 antibody CD antibody CD152 antigen antibody CD152 isoform antibody Celiac disease 3 antibody CELIAC3 antibody CTLA-4 antibody Cytotoxic T cell associated 4 antibody Cytotoxic T lymphocyte associated serine esterase 4 antibody GRD4 antibody GSE antibody ICOS antibody IDDM12 antibody Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody OTTHUMP00000216623 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-CTLA4 | |||
|
CTLA4-101AP | |||
|
CTLA4-FITC | |||
|
PC-CTLA4 | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.