HMGB1 Positive Control

General Information

Product

HMGB1 Positive Control

Description

Western Blot Positive Control High mobility group protein B1

Verified Applications

WB

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Protein

Uniprot #

P09429

Overview

Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids.

Molecular Function

bubble DNA binding

chemoattractant activity

C-X-C chemokine binding

cytokine activity

damaged DNA binding

DNA binding, bending

DNA binding transcription factor activity

DNA polymerase binding

double-stranded DNA binding

four-way junction DNA binding

integrin binding

lipopolysaccharide binding

lyase activity

phosphatidylserine binding

RAGE receptor binding

repressing transcription factor binding

RNA binding

single-stranded DNA binding

supercoiled DNA binding

transcription factor binding

Subcellular Location

Extracellular region or secreted, nucleus, endosome, plasma membrane, chromosome, cytoplasm, endoplasmic reticulum-golgi intermediate compartment

Expression

Ubiquituous. Expressed in platelets.

Structure

Belongs to the HMGB family.

Alternative Nomenclature

Amphoterin antibody

Chromosomal protein, nonhistone, HMG1 antibody

High mobility group box 1 antibody

High mobility group protein 1 antibody

High mobility group protein B1 antibody

high-mobility group (nonhistone chromosomal) protein 1 antibody

HMG-1 antibody

HMG3 antibody

HMGB 1 antibody

NONHISTONE CHROMOSOMAL PROTEIN HMG1 antibody

SBP 1 antibody

Sulfoglucuronyl carbohydrate binding protein antibody