General Information
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Product
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EFEMP1 Antibody
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Description
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Affinity Purified EGF-containing fibulin-like extracellular matrix protein 1 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic cyclic peptide corresponding to N terminal amino acids 25-42 of Human EFEMP1, peptide was covalently modified.
Sequence:
TYTQCTDGYEWDPVRQQC
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Accession #
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NCBI: XP_005264262.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.65 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:100 |
Immunoprecipitation
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1:200
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Western Blot
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1:500. Predicted molecular weight 60 kDa
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Protein
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Uniprot #
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UPI000387D485
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Overview
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Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
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Molecular Function
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Calcium
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Subcellular Location
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Secreted; Extracellular space
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Expression
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In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina.
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Structure
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Interacts with ECM1. Interacts with TIMP3.
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Alternative Nomenclature
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DHRD antibody
Doyne honeycomb retinal degeneration antibody
DRAD antibody
EFEMP 1 antibody
Epidermal growth factor containing fibulin like extracellular matrix protein 1 antibody
FBLN3 antibody
Fibrillin like antibody
FIBULIN 3 antibody
FLJ35535 antibody
Heat shock 70 KD protein 1 antibody
MGC111353 antibody
MLVT antibody
T16 protein antibody
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