General Information |
|
Product |
RIPK5 Antibody |
Description |
Dual serine/threonine and tyrosine protein kinase Antibody |
Verified Applications |
ELISA, IMM, WB |
Host |
Rabbit |
Species Cross Reactivity |
Bovine, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 200-250 on human Dual serine/threonine and tyrosine protein kinase protein (RIPK5). |
Accession # |
GenBank: Q6XUX3.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55 µg/µl in antibody stabilization buffer |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. |
Molecular Function |
ATP binding; Protein serine/threonine kinase activity; Protein tyrosine kinase activity; ATP-binding; Nucleotide-binding |
Subcellular Location |
Cell junction, Cell membrane, Cytoplasm, Membrane |
Expression |
Predominantly expressed in skeletal muscle and testis. Expressed in basolateral and apical membranes of all tubular epithelia. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional ureteric epithelium and in the ureteric smooth-muscle cells. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines. |
Structure |
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. |
Alternative Nomenclature |
DSTYK antibody Dual serine/threonine and tyrosine protein kinase antibody Dusty PK antibody Dusty protein kinase antibody HDCMD38P antibody KIAA0472 antibody Receptor interacting protein kinase 5 antibody Receptor interacting serine/threonine protein kinase 5 antibody RIP homologous kinase antibody RIPK5 antibody SgK496 antibody Sugen kinase 496 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
RIPK5-501AP | |||
|
P-RIPK5 | |||
|
RIPK5-BIOTIN | |||
|
PC-RIPK5 | |||
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