General Information
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Product
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CMT Antibody
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Description
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Affinity Purified Protein-S-isoprenylcysteine O-methyltransferase Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 230-284 on human Protein-S-isoprenylcysteine O-methyltransferase.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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O60725
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Overview
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Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
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Molecular Function
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Methyltransferase
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Subcellular Location
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Endoplasmic reticulum membrane; Multi-pass membrane protein
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Expression
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Ubiquitous
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Structure
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Belongs to class VI-like SAM-bidning methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family
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Alternative Nomenclature
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fcmt
HSTE14
Icmt
Isoprenylcysteine carboxylmethyltransferase
MST098
pcCMT
Prenylcysteine carboxyl methyltransferase
Protein-S-isoprenylcysteine O-methyltransferase
STE14
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