General Information
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Product
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BST2 Positive Control
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Description
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Western Blot Positive Control Bonemarrow stromal antigen 2
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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GenBank: BAD96844
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500-1:1,000
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Protein
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Uniprot #
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Q10589
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Overview
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IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.
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Molecular Function
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Antiviral defense; B-cell activation; Immunity; Innate immunity
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Subcellular Location
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Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane
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Expression
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Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.
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Structure
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Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.
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Alternative Nomenclature
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Bone marrow stromal antigen 2 antibody
Bone marrow stromal cell antigen 2 antibody
BST 2 antibody
CD 317 antibody
CD317 antigen antibody
HM1.24 antigen antibody
NPC A 7 antibody
Tetherin antibody
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