Adeno-Associated Virus Capsid Protein Blocking Peptide

Catalog no. P-AAVCAP-112 · Research Use Only

$155 per 250 µg. Ships within 2–3 business days from the U.S.

P-AAVCAP-112 — affinity-purified Rabbit antibody against Adeno-Associated Virus Capsid Protein. Validated for Immunodepletion, Immunocompetition. Reacts with Vi

Specifications

Catalog numberP-AAVCAP-112
TargetAdeno-Associated Virus Capsid Protein
ReactivityVirus
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide corresponding to a region of the adeno-associated virus capsid protein.
Size250 µg
Storage-20°C
UniProtP03135

About this target

Adeno-Associated Virus Capsid Protein Blocking Peptide is the antigenic blocking peptide for the Adeno-Associated Virus Capsid Protein antibody AAVCAP-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, VP2 and VP3 which differ in their N-terminus. The capsid encapsulates the genomic ssDNA. Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Subcellular location: Virion. Host nucleus, host nucleolus. Note=Capsid proteins are first observed in the host nucleolus where capsid assembly may occur, and then are present over the whole nucleoplasm where encapsidation of the viral DNA takes place.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.