Adeno-Associated Virus Capsid Protein Positive Control
Catalog no. PC-AAVCAP · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-AAVCAP — affinity-purified Rabbit antibody against Adeno-Associated Virus Capsid Protein. Validated for WB. Reacts with Virus.
Specifications
| Catalog number | PC-AAVCAP |
|---|---|
| Target | Adeno-Associated Virus Capsid Protein |
| Reactivity | Virus |
| Applications | WB |
| Conjugate | Unconjugated |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | P03135 |
About this target
Adeno-Associated Virus Capsid Protein Positive Control is a Western blot positive control for Adeno-Associated Virus Capsid Protein antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, VP2 and VP3 which differ in their N-terminus. The capsid encapsulates the genomic ssDNA. Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Subcellular location: Virion. Host nucleus, host nucleolus. Note=Capsid proteins are first observed in the host nucleolus where capsid assembly may occur, and then are present over the whole nucleoplasm where encapsidation of the viral DNA takes place.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.