ALCAM Blocking Peptide
Catalog no. P-ALCAM-101MAB · Research Use Only
$200 per 250 µg. Ships within 2–3 business days from the U.S.
P-ALCAM-101MAB — affinity-purified Rabbit antibody against ALCAM. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-ALCAM-101MAB |
|---|---|
| Target | ALCAM |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to amino acids within region 125-175 on human ALCAM protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q13740 |
About this target
ALCAM Blocking Peptide is the antigenic blocking peptide for the ALCAM antibody ALCAM-101MAB. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation. Required for normal hematopoietic stem cell engraftment in the bone marrow. Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Note=Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells.
Documents
Related products
- ALCAM Antibody (ALCAM-101MAB)
- ALCAM Antibody BIOTIN (ALCAM-101MAB-BIOTIN)
- ALCAM Antibody FITC (ALCAM-101MAB-FITC)
- ALCAM Antibody (ALCAM-112MAB)
- ALCAM Antibody BIOTIN (ALCAM-112MAB-BIOTIN)
- ALCAM Antibody FITC (ALCAM-112MAB-FITC)
- ALCAM Blocking Peptide (P-ALCAM-112MAB)
- ALCAM Positive Control (PC-ALCAM-101MAB)
- ALCAM Positive Control (PC-ALCAM-112MAB)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.