ALCAM Positive Control
Catalog no. PC-ALCAM-112MAB · Research Use Only
$250 per 5 applications. Ships within 2–3 business days from the U.S.
PC-ALCAM-112MAB — affinity-purified Rabbit antibody against ALCAM. Validated for WB.
Specifications
| Catalog number | PC-ALCAM-112MAB |
|---|---|
| Target | ALCAM |
| Applications | WB |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to amino acids within region 360-410 on human ALCAM protein. |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | Q13740 |
About this target
ALCAM Positive Control is a Western blot positive control for ALCAM antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation. Required for normal hematopoietic stem cell engraftment in the bone marrow. Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Note=Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.