ATG16L1 Antibody

Catalog no. ATG16L1-101AP · Research Use Only

$285 per 100 µg. Ships within 2–3 business days from the U.S.

ATG16L1-101AP — affinity purified Rabbit antibody against ATG16L1. Validated for ELISA, IHC, IP, WB. Reacts with Human, Mouse, Rat.

Specifications

Catalog numberATG16L1-101AP
TargetATG16L1
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, IP, WB
ConjugateUnconjugated
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 558-607 on human Autophagy-related protein 16-1.
Size100 µg
Storage-20°C
UniProtQ676U5

About this target

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elon. Homooligomer. Interacts with WIPI2, FIP200 and ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Interacts with RAB33B. Interacts with TMEM. Subcellular location: Cytoplasm, Preautophagosomal structure membrane, Peripheral membrane protein.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.