ATG16L1 Positive Control

Catalog no. PC-ATG16L1 · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-ATG16L1 — affinity-purified Rabbit antibody against ATG16L1. Validated for WB.

Specifications

Catalog numberPC-ATG16L1
TargetATG16L1
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtQ676U5

About this target

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elon. Homooligomer. Interacts with WIPI2, FIP200 and ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Interacts with RAB33B. Interacts with TMEM. Subcellular location: Cytoplasm, Preautophagosomal structure membrane, Peripheral membrane protein.

Documents

Related products

FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.