Bile Acid Receptor NR1H4 Antibody

Catalog no. NR1H4-101AP · Research Use Only

$285 per 100 µg. Ships within 2–3 business days from the U.S.

NR1H4-101AP — affinity purified Rabbit antibody against Bile Acid Receptor NR1H4. Validated for ELISA, IP, WB. Reacts with Human.

Specifications

Catalog numberNR1H4-101AP
TargetBile Acid Receptor NR1H4
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman
ApplicationsELISA, IP, WB
ConjugateUnconjugated
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 1-50 on huma Bile acid receptor / NR1H4 / FXR A3-4 protein.
Size100 µg
Storage-20°C
UniProtQ96RI1

About this target

Ligand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, deoxycholic acid (DCA) and allocholic acid (ACA). Plays a essential role in BA homeostasis through the regulation of genes involve. Zinc-finger. Subcellular location: Nucleus. Expression: Liver and hepatocyte-related cells express mainly FXRalpha1-type isoforms with isoform 3 and isoform 4 in approximately equal proportions. In intestine and kidney mainly FXRalpha2-type isoforms are expressed with isoform 1 and isoform 2 in approximately e.

Documents

Related products

FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.