Bile Acid Receptor NR1H4 Blocking Peptide
Catalog no. P-NR1H4 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-NR1H4 — affinity-purified Rabbit antibody against Bile Acid Receptor NR1H4. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-NR1H4 |
|---|---|
| Target | Bile Acid Receptor NR1H4 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 1-50 on huma Bile acid receptor / NR1H4 / FXR A3-4 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q96RI1 |
About this target
Ligand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, deoxycholic acid (DCA) and allocholic acid (ACA). Plays a essential role in BA homeostasis through the regulation of genes involve. Zinc-finger. Subcellular location: Nucleus. Expression: Liver and hepatocyte-related cells express mainly FXRalpha1-type isoforms with isoform 3 and isoform 4 in approximately equal proportions. In intestine and kidney mainly FXRalpha2-type isoforms are expressed with isoform 1 and isoform 2 in approximately e.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.