CARD15 Antibody FITC
Catalog no. NOD2-FITC · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
NOD2-FITC — affinity purified Rabbit antibody against CARD15. Validated for ELISA, IP, WB. Reacts with Mouse, Rat.
Specifications
| Catalog number | NOD2-FITC |
|---|---|
| Target | CARD15 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | FITC |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 700-780 on mouse Nucleotide-binding oligomerization domain-containing protein 2. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | Q8K3Z0 |
About this target
Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex,. The ATG16L1-binding motif mediates interaction with ATG16L1. Intramolecular interactions between the N-terminal moiety and the leucine-rich repeats (LRR) may be important for autoinhibition in the absence of activating signal. In the absence of LRRs, the. Subcellular location: Cytoplasm Membrane Basolateral cell membrane.
Documents
Related products
- CARD15 Antibody (NOD2-201AP)
- CARD15 Antibody BIOTIN (NOD2-BIOTIN)
- CARD15 Blocking Peptide (P-NOD2)
- CARD15 Positive Control (PC-NOD2)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.