CARD15 Blocking Peptide
Catalog no. P-NOD2 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-NOD2 — affinity-purified Rabbit antibody against CARD15. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-NOD2 |
|---|---|
| Target | CARD15 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 700-780 on mouse Nucleotide-binding oligomerization domain-containing protein 2. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q8K3Z0 |
About this target
Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex,. The ATG16L1-binding motif mediates interaction with ATG16L1. Intramolecular interactions between the N-terminal moiety and the leucine-rich repeats (LRR) may be important for autoinhibition in the absence of activating signal. In the absence of LRRs, the. Subcellular location: Cytoplasm Membrane Basolateral cell membrane.
Documents
Related products
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.