Claudin-18 Antibody BIOTIN

Catalog no. CLDN18-BIOTIN · Research Use Only

$375 per 100 µg. Ships within 2–3 business days from the U.S.

CLDN18-BIOTIN — affinity purified Rabbit antibody against CLDN18. Validated for ELISA, WB. Reacts with Human, Mouse, Rat.

Specifications

Catalog numberCLDN18-BIOTIN
TargetCLDN18
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationsELISA, WB
ConjugateBIOTIN
PurityAffinity Purified
Immunogen(amino acid region 12-61 of Claudin-18)
Size100 µg
Storage-20°C
UniProtP56856

About this target

Claudin-18 Antibody BIOTIN is the biotin-conjugated version of the CLDN18 antibody CLDN18-101AP, an affinity-purified rabbit polyclonal used in ELISA, WB and reactive with Human, Mouse, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Involved in alveolar fluid homeostasis via regulation of alveolar epithelial tight junction composition and therefore ion transport and solute permeability, potentially via downstream regulation of the actin cytoskeleton organization and beta-2-adrenergic signaling. Required for lung alveolarization and maintenance of the paracellular alveolar epithelial barrier. Acts to maintain epithelial progenitor cell proliferation and organ size, via regulation of YAP1 localization away from the nucleus and thereby restriction of YAP1 target gene transcription. Subcellular location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.