Claudin-18 Blocking Peptide
Catalog no. P-CLDN18 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-CLDN18 — affinity-purified Rabbit antibody against CLDN18. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-CLDN18 |
|---|---|
| Target | CLDN18 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 12-61 of human CLDN18 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P56856 |
About this target
Claudin-18 Blocking Peptide is the antigenic blocking peptide for the CLDN18 antibody CLDN18-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Involved in alveolar fluid homeostasis via regulation of alveolar epithelial tight junction composition and therefore ion transport and solute permeability, potentially via downstream regulation of the actin cytoskeleton organization and beta-2-adrenergic signaling. Required for lung alveolarization and maintenance of the paracellular alveolar epithelial barrier. Acts to maintain epithelial progenitor cell proliferation and organ size, via regulation of YAP1 localization away from the nucleus and thereby restriction of YAP1 target gene transcription. Subcellular location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Documents
Related products
- Claudin-18 Antibody (CLDN18-101AP)
- Claudin-18 Antibody BIOTIN (CLDN18-BIOTIN)
- Claudin-18 Antibody FITC (CLDN18-FITC)
- Claudin-18 Positive Control (PC-CLDN18)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.