CTLA4 Blocking Peptide
Catalog no. P-CTLA4 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-CTLA4 — affinity-purified Rabbit antibody against CTLA4. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-CTLA4 |
|---|---|
| Target | CTLA4 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 150-200 on human CTLA4 protein |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P16410 |
About this target
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family lingands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory correceptor CD28. Homodimer; disfulfide-linked. Subcellular location: Cell membrane; Single pass type I membrane protein. Expression: Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory correceptor, on the cell surface following activation.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.