CTLA4 Positive Control

Catalog no. PC-CTLA4 · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-CTLA4 — affinity-purified Rabbit antibody against CTLA4. Validated for WB.

Specifications

Catalog numberPC-CTLA4
TargetCTLA4
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtP16410

About this target

Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family lingands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory correceptor CD28. Homodimer; disfulfide-linked. Subcellular location: Cell membrane; Single pass type I membrane protein. Expression: Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory correceptor, on the cell surface following activation.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.