DAPK2 Antibody BIOTIN

Catalog no. DAPK2-BIOTIN · Research Use Only

$375 per 100 µg. Ships within 2–3 business days from the U.S.

DAPK2-BIOTIN — affinity purified Rabbit antibody against DAPK2. Validated for ELISA, IHC, IP, WB. Reacts with Human, Mouse, Rat.

Specifications

Catalog numberDAPK2-BIOTIN
TargetDAPK2
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, IP, WB
ConjugateBIOTIN
PurityAffinity Purified
ImmunogenSynthetic peptide take within amino acid region 300-350 on mouse Death-associated protein kinase 2 protein.
Size100 µg
Storage-20°C
UniProtQ8VDF3

About this target

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capable of regulating both type I apoptotic and type II autophagic cell death signals. The former i. The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core. Subcellular location: Cytoplasm autophagosome lumen. Expression: Expressed in peritubular interstitial cells of the renal cortex (PubMed:24906443). Isoform 1 is found in the adult brain while isoform 2 is expressed in brains of embryos and young mice (at protein level) (PubMed:21408167).

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.