DAPK2 Blocking Peptide
Catalog no. P-DAPK2 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-DAPK2 — affinity-purified Rabbit antibody against DAPK2. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-DAPK2 |
|---|---|
| Target | DAPK2 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide take within amino acid region 300-350 on mouse Death-associated protein kinase 2 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q8VDF3 |
About this target
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capable of regulating both type I apoptotic and type II autophagic cell death signals. The former i. The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core. Subcellular location: Cytoplasm autophagosome lumen. Expression: Expressed in peritubular interstitial cells of the renal cortex (PubMed:24906443). Isoform 1 is found in the adult brain while isoform 2 is expressed in brains of embryos and young mice (at protein level) (PubMed:21408167).
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.